Life Sciences News Update / Bio Online newsletter at
Tue Feb 26 20:59:54 EST 2002 Life Sciences News Update
February 27, 2002

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1.  Science News: “Mighty Mice”
2.  InFocus:  “Real-Time PCR: Emerging Applications”
3.  Career Center:  Set up your free personal profile today
4.  Jobs of the Week:  “Research Associate” and others
5.  Market Research:  “Drug Discovery Industry Review”
6.  Featured Software:  “Biotechnix 3D 1.1” and others


-Muscle Gene Influences Fat Storage
Previous studies found that mice without myostatin are muscle-bound 
“mighty mice.” Now scientists show that mice without the protein, 
even mice that usually become obese, gain much less fat as they age.

-Path to Folded Protein Unpredictable
New support for a more heterogeneous model of protein folding comes in a
paper published in the Proceedings of the National Academy of Sciences. 
The work suggests quite strongly that folding is a far richer phenomenon
than previously thought.

-Tree Rings Link Historic Epidemics to Drought
Tree ring reconstruction of rainfall may provide insight into some of the
epidemics that decimated the native population of Mexico shortly after the
arrival of Europeans. The evidence points to hemorrhagic fevers caused by an
indigenous virus instead of diseases introduced from the Old World.

-Regulating Biotech Crops
The National Academy of Sciences published a major report last week on the 
environmental effects of genetically modified plants.

-Onset Genes for Alzheimer's and Parkinson's
Duke University Medical Center researchers have identified a group of 
chromosomal regions that could be responsible for controlling the onset of 
Alzheimer's or Parkinson's diseases.

-Notes on Venture Capital Agreements
What Happens When Your Entrepreneurial Idea Finally Gets Funding?

-Marketing Strategy, Targeted Marketing and the Role of Primary Research
Even at some of the most successful pharmaceutical companies, the enthusiasm 
of excited scientists can lead them to think their products will be so good 
that they'll “jump off the shelves” and sell themselves. To realize a 
product's full potential, however, companies must support the product with 

To view Industry news, visit:

To view Research news, visit:


1)  “Real-Time PCR:  Emerging Applications”
Broadcast Wednesday, February 13, 2002

*Click here to listen to the audio recording:

*Click here to view the transcript (HTML version):

2)  “Advances in DNA & RNA Diagnostics”
Broadcast Thursday, January 31, 2002

*Click here to listen to the audio recording:

*Click here to view the PDF transcript:

*To view the PDF transcript of an interview with Mark Akeson 
on the use of nanopore technology to analyze DNA, click here:

3)  To view the PDF transcript of an interview with Gregory 
Gibson on his efforts to quantify cDNA microarray data, click here:

*For information on how to tune in to’s live webcasts, go to:

*To view past InFocus Webcast recordings and transcripts, go to:

=========================================================================== offers the most comprehensive online Career Center in the life
sciences industry.

Set up your free personal profile today at:

Browse all job postings:


Look at what’s new in the Career Center this week:

1.  Upstate Biotechnology:  Technical Support Representative

2.  Vertex Pharmaceuticals:  Investigator/Associate Scientist

3.  DHR International:  Director of Novel Probe Systems

4.  The Western Pennsylvania Hospital:  Research Associate

5.  UCSF-Division of Infectious Diseases:  Postdoctoral Fellowship

Browse all jobs at

=========================================================================== offers the most comprehensive collection of market research
available on the web. Check out these latest additions:

-High Growth Diagnostic Market Worldwide II
Which diagnostic markets will experience explosive growth over the next few
years? What forces are shaping these sectors? How will new technology change
diagnostic medical practice? High Growth Diagnostic Markets Worldwide II
analyzes the underlying trends and factors, to understand the drivers of
market growth, and which sectors and technologies are likely to prosper

-The New Future of Biotechnology: Enabling Technologies and Star Products
Biotechnology is gearing up to create a revolution in health care.  
This report provides a range of information from detailed market 
analyses through industry trends to quantify and qualify the impact
of two leading technologies of the biotechnology industry – genomics
(including proteomics, pharmacogenomics and bioinformatics) 
and therapeutic antibodies.

-Drug Discovery Industry Review
The very foundations of drug discovery research are being rapidly
transformed by robotics, high throughput systems, automated assays, and
advanced software systems. This anthology keeps readers abreast on the
latest news on the industry players, regulations, markets and overseas
developments in the drug industry.

=========================================================================== offers a very comprehensive selection of Life Science related
software. Check out these latest additions:

-HyperChem Professional Release 6.0
HyperChem is a sophisticated molecular modeling environment that is known
for its quality, flexibility, and ease of use. Uniting 3D visualization and
animation with quantum chemical calculations, molecular mechanics, and
dynamics, HyperChem puts more molecular modeling tools at your fingertips
than any other Windows program.

-Biotechnix 3D 1.1
Biotechnix 3D 1.1 software introduces the next generation of bioinformatics
software with powerful new features that offer something for every
researcher. Delivering the broadest and most productive toolset available,
Biotechnix 3D helps to explore your creativity, work at peak efficiency, and
achieve the highest quality results for your publications.

-Genamics Expression
Expression is a revolutionary new application for DNA and protein sequence
analysis. Utilizing a novel interface, Expression makes complex
computational analyses of sequence information incredibly simple. Expression
uses the very latest computing technology to set new standards in the way
sequences are analyzed.

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