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Life Sciences News Update

Bio.com / Bio Online newsletter at bio.com
Tue Mar 19 20:54:26 EST 2002


Bio.com Life Sciences News Update
March 20, 2002

Produced by Bio Online®
The Life Sciences Portal(tm)
www.bio.com | www.bioprotocol.com

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CONTENTS:
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1.  Science News: “Gravity in the Brain”
2.  InFocus:  “BioIT: Knowledge Management”
3.  Bio.com Job Fair:  May 4, 2002 @ Oakland Marriott Convention Center
4.  Jobs of the Week:  “Manager of Biostatistics” and others
5.  Market Research:  “Pharmaceutical/Biotech R&D Alliances”
6.  Featured Software:  “SCIENTIST” and others

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1.  SCIENCE NEWS
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-Gravity in the Brain
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=1
Playing catch is easy. Kids and even their parents can do it. Keep your 
eyes on the ball and -- if you don't think too hard -- your hand will grab
it in mid-air. It's simple, really. Or is it? In fact, playing catch is more
complicated than it appears.

-The Building Blocks of Erection
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=2
A team of Hopkins scientists has greatly advanced the science of penile
erection, showing for the first time the mechanism for continued production
of nitric oxide that maintains an erection over time.

-How Hummingbirds Regulate Water Intake
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=3
Scientists have long been fascinated with how hummingbirds -- one of 
Earth's smallest, warm-blooded vertebrates -- can nutritionally maintain
their high-metabolic daily lifestyles, let alone fly thousands of miles
during migration.

-Virtual Cells Help Unravel Cell Motion
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=4
A "virtual cell" that biologists can use to test theories about how cells 
move has been created by University of California, Davis, mathematician Alex 
Mogilner and colleagues at UC Berkeley, Florida State University and the 
Medical Research Council laboratories in Mill Hill, England.

-Hamsters Boost Immune Function in Winter
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=5
A new study has found that Siberian hamsters boost their immune function 
during the winter in order to help them cope with the seasonal stresses of 
cold weather and limited food.

-Anti-Cloning Disinformation?
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=6
Desperate opponents try to frighten lawmakers with bogus scares.

-Featured Molecule: Bacteriorhodopsin
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=7
Photosynthesis requires a complex collection of molecular antennas and 
photosystems. However, some bacteria have found a simpler solution to 
capturing sunlight.


To view Industry news, visit:
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml

To view Research news, visit:
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml


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2.  INFOCUS WEBCAST
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1)  “BioIT: Knowledge Management”
Broadcast Thursday, March 12, 2002

*Click here to listen to the audio recording:
http://chat.bio.com:8000/audio/bioit_020307.mp3

2)  “Real-time PCR: Emerging Applications”
Broadcast Wednesday, February 13, 2002

*Click here to listen to the audio recording:
http://chat.bio.com:8000/audio/rtpcr_021302.mp3

*Click here to view the PDF transcript:
http://www.bio.com/file_temp/realtime.pdf


*For information on how to tune in to Bio.com’s live webcasts, go to:
http://www.bio.com/Redirectors/LinkRedirect01_23.jhtml?link=10

*To view past InFocus Webcast recordings and transcripts, go to:
http://www.bio.com/newsfeatures/newsfeatures_fochives.jhtml


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3.  BIO.COM JOB FAIR
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-When: 

May 4th, 2002
10am – 3 pm

-Location:

Oakland Marriott Convention Center
550 10th Street
Oakland, CA 94607

Looking for a job?  Planning for the future?

Find the right job at the Bio.com Job Fair and network with top notch 
biotechnology and pharmaceutical representatives.  Employers in the
biopharmaceutical industry are out there looking for candidates with
your background.  The admission for job seekers is free.

For more information regarding the job fair, please visit:
http://www.bio.com/careercenter/careercenter_jobfair.jhtml


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4.  JOBS OF THE WEEK
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Look at what’s new in the Bio.com Career Center this week:

1.  PPD (Pharmaceutical Product Development):  Manager of Biostatistics
http://career.bio.com/pages/jobsearch.cfm?object=5&job=776838&action=View

2.  Metabolex, Inc.:  Research Scientist, Insulin Resistance
http://career.bio.com/pages/jobsearch.cfm?object=5&job=777919&action=View

3.  Essential Therapeutics:  Biochemist, Bioanalysis and Drug Metabolism
http://career.bio.com/pages/jobsearch.cfm?object=5&job=776698&action=View

4.  Specialty Laboratories:  Medical Technologists
http://career.bio.com/pages/jobsearch.cfm?object=5&job=771474&action=View

5.  Inhale:  Director, Project Management
http://career.bio.com/pages/jobsearch.cfm?object=5&job=770974&action=View

6.  Hamamatsu Corporation:  Product Manager
http://career.bio.com/pages/jobsearch.cfm?object=5&job=777859&action=View

7.  Vical, Inc.:  Development Associate
http://career.bio.com/pages/jobsearch.cfm?object=5&job=777921&action=View

8.  Staubach and Associates:  Validation Engineer
http://career.bio.com/pages/jobsearch.cfm?object=5&job=777831&action=View


Click here to browse all jobs from Bio.com’s Career Center:
http://career.bio.com/pages/featured.cfm?1


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5.  MARKET RESEARCH
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Bio.com offers the most comprehensive collection of market research
available on the web. Check out these latest additions:

-Pharmaceutical/Biotech R&D Alliances
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=8
Streamline your research and your ability to make timely, strategic
decisions. This AdvanceTech Monitor (ATM) report gives you a unique
advantage. Not only do you receive over 25 chapters of expert opinion on the
technology and business strategies behind Predictive Toxicology, but you
also receive over 150 tables and figures to illustrate points of discussion
and over 150 weblinks to key internet sources of information.

-In Silico Technology - The Drivers and Challenges of this Promising
Field - Executive Briefing
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=9
An estimated 12-15 years and more than $500 million is needed to develop a
new drug today. Over $150 million of that is attributed to drug and
experiment failures, with a clinical trial failure rate of over 80%. This
industry paradigm necessitates the use of other technologies to minimize the
time, cost, and risk of drug development. In silico methods are beginning to
offer some interesting alternatives to the current process.

-Bioinformatics: Getting Results in the Era of High-Throughput Genomics
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=10
Bioinformatics will be one of the keys to success for companies applying
genomic tools to drug discovery and development. Demand for greater
flexibility, better integration, and higher-value analytical tools is
increasing. This report describes the current and emerging role of
bioinformatics in genomics-based drug discovery and development, the
existing tools and those under development, and the strategies that
companies are pursuing to meet future demands.


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6.  FEATURED SOFTWARE
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Bio.com offers a very comprehensive selection of Life Science related
software. Check out these latest additions:

-HyperChem Release 7
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=11
HyperChem is a sophisticated molecular modeling environment that is known
for its quality, flexibility, and ease of use. HyperChem Release 7
incorporates even more powerful computational chemistry tools than ever
before, as well as newly incorporated modules, additional basis sets, new
drawing capabilities and more.

-SCIENTIST
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=12
SCIENTIST is dedicated exclusively to solving systems of model equations and
fitting experimental data. A common activity in both teaching and research
is the analysis of experimentally generated data. Data analysis requires
evaluating how well theoretical equations predict fitting of model equations
to data.

-The Hypothetical Active Site Lattice (Doweyko)-HASL
http://www.bio.com/Redirectors/LinkRedirect03_19.jhtml?link=13
Classical QSAR strategy necessarily limits relationships to a defined
structural series or class. The real challenge is to go beyond known QSAR
methodology and handle relationships in 3D space, i.e., relate structures
from differing classes to activity in a quantitative way by means of their
actual shapes and properties. Work that was begun in 1986 culminated in the
discovery and development of a novel 3D-QSAR methodology, the Hypothetical
Active Site Lattice (HASL).


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