Sequencing using Gene Chips

Rifat Rifat
Tue Jul 22 16:23:38 EST 1997


Hi,

	I would be grateful for any information regarding the use of
DNA gene chips for sequencing.

I am interested in the followings :

(1) Can you sequences from mRNA or does it only work on DNA
(2) How clean does your DNA has to be?
(3) How much does it cost to manufacture a chip via VLSI?
(4) How does the detections system work assuming that the technology is
    based on hybridisation?
(5) What is the maximum length that one can sequence on a chip with no
    problems?
(6) How does the chip cope with heterozygote detection?


Thanks.

Rifat.



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