Q: searching for phosphorylation sites

Steve Miller Sgmiller at netcom.com
Thu Dec 8 11:28:56 EST 1994


In Article <ehom1-081294001714 at mac04.parrishd.swarthmore.edu>,
ehom1 at cc.swarthmore.edu (Erik Forbes Y. Hom '95) wrote:
>Hi netters, Could anyone here tell the best way to search for potential
>phosphorylation sites or sequence homologies to phosphorylated regions. 
>Are there programs that do this for you?  What would be the best way to
>proceed?
>Thanks in advanced for your help!
>
>erik

On the Macintosh you can try MacPattern by Rainer Fuchs. The program is
freeware and uses the Prosite database of consensus sequences, motifs, and
patterns. The author's e-mail address is (was?) fuchs at embl-heidelberg.de. A
number of consensus phosphorylation sites are in this database
(cAMP-dependent kinase, PKC, etc.) of >900 entries. The program will pull up
a description of the motif and give relevant references in the literature.
The Prosite database is also accessible through UNIX-based molecular biology
packages.

steve




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