artifial sequence generator

David R. Maddison dmaddsn at
Thu Mar 17 14:28:48 EST 1994

In article <1994Mar16.105322.1 at>, roberto at

>  Does anybody know a program that generates artificial DNA sequences following
> a certain evolution rate.

MacClade 3 will allow you do build a phylogenetic tree on the screen,
and ask to have up to 16,000 nucleotides evolve up the branches of the
tree.  You can specify a matrix of probabilities of change along 
each segment of the tree, and can specify the branch lengths (by 
designating the number of segments along a branch).  The collection of
sequences produced can then be saved in a number of different formats.

David Maddison
University of Arizona        dmaddsn at

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