Sequence comparison

Bob Wildin, M.D. rwildin at beach.utmb.edu
Wed Nov 23 16:10:26 EST 1994


I did some of this a few years ago.  The best I found was to combine
dot-matrix comparisons with homology searches with non-default
parameters.  I used mostly GenePro software for PC.  Unfortunately,
this gave no indication of statistical importance, and one must still
do the wet-lab studies to see if there is any significance there. 
Overall, I found this approach to defining potential regulatory
sequences of little practical use.




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