Software to detect linkage disequil.?

[David MacHugh]

Hi,


Is anybody of aware of a program that provides statistical analysis of
allelic association (linkage or gametic disequilibrium) between multialleic
genetic markers for population data? A program capable of generating random
reshuffled bilocus genotypic distributions would be particularly desirable.
This would create a synthetic distribution to compare the observed data
with and would allow meaningful statistical assessment of populations with
small sample sizes (approx. 50 individuals).
We have data from a large number of microsatellites typed in 20
populations, hence source code would be useful as we could then port it to
a DEC alpha to cut down the runtime.

I would try a develop a program myself except that I am trying to finish my
PhD thesis and I can't write a line of code ;-)

Thanks in advance for your help.

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