Mult. sequence align. progr. for Windows/DOS?

Paul Caron caron at intbio.com
Fri Oct 21 20:37:47 EST 1994


Get Macaw from the NCBI for Windows or Macs.

Excerpts from the README.TXT file:

MACAW is a program for locating, analyzing, and editing blocks of localized 
sequence similarity among multiple seqences and linking them into a 
composite multiple alignment.

REFERENCES

Gregory D. Schuler, Stephen F. Altschul, and David J. Lipman (1991). A 
   Workbench for  Multiple Alignment Construction and Analysis.  Proteins 
   Struct. Funct. Genet. 9, 180-190.

Charles E. Lawrence, Stephen F. Altschul, Mark S. Boguski, Jun S. Liu, Andrew 
   F. Neuwald, and John C. Wootton (1993).  Detecting  Subtle Sequence 
   Signals:  A Gibbs Sampling Strategy for Multiple Alignment.  Science  262, 
   208-214.

Samuel Karlin and Stephen F. Altschul (1990).  Methods for Assessing the 
   Statistical Significance of Molecular Sequence Features by Using General 
   Scoring Schemes. Proc. Natl. Acad. Sci. USA  87, 2264-2268 (1990)

FTP DOWNLOADING INSTRUCTIONS

The program is available for the Macintosh and several flavors of 
Microsoft Windows.  All of them may be downloaded from NCBI's anonymous
FTP server (ncbi.nlm.nih.gov).  Each version is stored in a seperate
directory as described below.

pub/macaw/win16
  This directory contains the 16-bit version of MACAW for Windows 3.1x and
  Windows for Workgroups 3.1x.  The file macawz.exe should be downloaded
  in binary mode.

pub/macaw/win32-intel
  This directory contains the 32-bit version of MACAW for systems based on
  the Intel family of processors.  It requires either Windows NT or a DOS-hosted
  version of Windows that also has the Win32s subsystem installed.  
  The file macawz.exe should be downloaded in binary mode.

pub/macaw/win32-alpha
  This directory contains the 32-bit version of MACAW for systems based on
  the DEC Alpha AXP processor and running Windows NT.  The file macawz.exe 
  should be downloaded in binary mode.

pub/macaw/mac-68k
  This directory contains the version of MACAW for Macintosh systems based on
  the 680x0 family of processors, but also runs on PowerMacs under emulation.  
  The file macaw.sea.hqx (HexBin format) should be downloaded to your mac.  
  Many Mac FTP programs automatcally convert HexBin files, so you will end 
  up with a file called macaw.sea.  If you do not have such a program, you
  will need to perform HexBin conversion yourself using a utility such as
  Stuffit or Compactor.




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