Antibody 3D Modeling

Hiroyoshi Ohba ohba at YL05HP.TB.NODA.SUT.AC.JP
Fri Oct 28 01:48:57 EST 1994


HELLO Netters;

        Is there any software which assembles three-dimesional structure of
antibody Fab?   Now, I am not familier with structural biology but like to
analyse the effect of molecular modification of antibody.  I have tried AbM
of Oxford Molecular Ltd which has been developed by Prof. Tony Rees's Lab. 
It works on the stand-alone Silicon Graphics and HP workstations. In my
case on assembling human Fab from its amino-acid sequence, enormous time
(days) was required for caliculation.  Would you suggest quicker softwares
on faster machines, or software employing other argorisms?  All of your
comments are welcomed.
### # # # # # #  #  #   #    #    #     #    #   #   #  #  #  #  #  # #  #
Hiroyoshi Ohba, Ph.D.
Laboratory of Immunology,
Department of Biological Science & Technology,
Science University of Tokyo
2641 Yamazaki, Noda, Chiba 278 Japan                               
Tel: 471-24-1501 ext. 4429      FAX: 471-25-1841             
e-mail: ohba at yl05hp.tb.noda.sut.ac.jp
(domain name is y-el-zero-5hp not y-one-owe-5hp, sorry) 
### # # # # # #  #  #   #    #    #     #    #   #   #  #  #  #  #  # #  #





More information about the Bio-soft mailing list