Protein modelling software for PowerMacs (was: (none))

Richard P. Grant rpgrant at
Mon Apr 8 15:49:32 EST 1996

In article <4kbe18$kdj at>, krasel at (Cornelius Krasel) writes:
> You might have seen on this newsgroup an announcement for the program
> "FoldIt Light" which should do what you want (I have never tried it). 
> However, do not expect any program to get a sequence as input and
> spew out a structure. The protein folding problem isn't yet solved.
> Rasmol, mentioned by somebody else, can only render existing structures, 
> but not calculate new ones. It is a (really nifty!) program for looking
> at molecules, not constructing new ones.

You are 100% correct Cornelius.  I would it were that simple to determine 
structure!  There are a number of ways of predicting secondary structure, if 
you have good homology with another proteins you can do this to about 80% 
accuracy with a program whose name escapes me, but I can look it up for you.
It's better rated than the stuff within GCG, but maybe that dooes not say 

PredictProtein at is possibly what I'm thinkin - Sanders and 
Rost did the algorithms.  Please correct me if I'm wrong.

> /* "Science is the game we play with God to find out what His rules are."  */

Well, that and for paying the bills ;-)
Richard P. Grant MA DPhil         rpgrant at
Nuffield Department of Obstetrics and Gynaecology, University of Oxford.   Fax +44 1 865 69141
Walk softly..... and carry an armoured tank division

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