Looking for antigenicity software

mathog at seqaxp.bio.caltech.edu mathog at seqaxp.bio.caltech.edu
Sun Jan 12 11:33:31 EST 1997


In article <5b0sa7$k0t at erika.cica.es>, bb1rofra at uco.es (Antonio Rodriguez Franco) writes:
>I am trying to raise polyclonal antibodies using a short oligopeptide
>stick to albumin.
>
>Is there any reliable software in which to test the antigenicity and
>surface probability of my sequence?

There is the program ANTIGENIC which is part of the EGCG package (which
means you also have to have GCG).

ANTIGENIC

     ANTIGENIC  looks  for potential antigenic regions using the method of
     Kolaskar.

ANTIGENIC
  DESCRIPTION

     Antigenic  predicts  potentially  antigenic  regions  of  a   protein
     sequence,  using the method  of Kolaskar and Tongaonkar  (1990); FEBS
     Letters  276:172-174  "A  semi-empirical  method  for  prediction  of
     antigenic determinants on protein antigens."

Regards,

David Mathog
mathog at seqaxp.bio.caltech.edu
Manager, sequence analysis facility, biology division, Caltech 




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