Pfam 2.1 Release

Ewan Birney birney at
Fri Oct 31 10:06:46 EST 1997


Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models.
Pfam families contain functional annotation and cross-references to
other databases. A paper on Pfam has been published in Proteins
28:405-420 (1997).

Pfam was recently mentioned in the Science Genome issue (Vol 278, No
5338).  This issue includes a poster about characterising gene families 
using a variety of methods, including Pfam.

Release 2.1 contains new annotation and corrections to some families
compared to release 2.0.  Pfam 2.1 is available on the web, offering
access to multiple sequence alignments and profile HMM searches.

  See URL

The release is available in flat file by anonymous ftp:


The Pfam consortium

More information about the Bio-soft mailing list