rls at ebi.ac.uk
Mon Mar 23 06:50:26 EST 1998
"Berke, Tamas" wrote in message
<205969B4B7A2D11181F600805FBB80EA05164A at chkd.evms.edu>...
>I recently learned that PC/Gene (latest version 6.85) is no longer
>by the developer.
>I was recommended OMIGA to replace it which is a new Win95-based program
>sequence database and basic manipulation.
>Still evaluating it, I am not convinced yet that OMIGA can really replace
>I might need to spend more time with OMIGA, however, in the meantime, I'd
>like to get some idea from you for a Win95 program for maintaining nt and
>sequence databases and performing basic analysis on those (incl. pairwise
>and multiple alignment, translation, database homology search).
>Thanks for your input.
This is an unofficial reply but I hope it helps.
Maintenance of nt and aa databases under windows: Why not try EMBL Search.
This program is a free database and query retrieval system for the MAC as
well as PCs running windows (3.1x, 95 and NT). Please check
and ftp.ebi.ac.uk/pub/software/dos. Alternatively contact kasia at ebi.ac.uk
who will be quite happy to provide more information.
1. Database homologies searches:fasta and blastall which can be found at
check: ftp.ebi.ac.uk, ncbi.nlm.nih.gov, ftp.virginia.edu and
2. Multiple alignments:
check clustalw and clustalx: ftp.ebi.ac.uk/pub/software/dos/clustalw
3. Paiwise alignments:
check Macaw from ncbi.nlm.nih.gov (also at the EBI ftp.ebi.ac.uk)
There are various site which permit you to do some of the thing you want on
The list is long but a little excursion will set you in the right track:
I do hope this helps,
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