Pfam Release 4.2
birney at sanger.ac.uk
Sat Aug 14 11:32:01 EST 1999
ANNOUNCING PFAM RELEASE 4.2
Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models.
Pfam families contain functional annotation and cross-references to
other databases. Query sequences can be searched against the Pfam
library of profile hidden Markov models at the web sites below.
Pfam 4.2 contains 1664 families. 61% of proteins in SWISSPROT 37
and TrEMBL 9 have at least one match to a Pfam family.
For interactive access and searching see URLs
The release is also available in flat file by anonymous ftp:
The Pfam HMM library is compatible with HMMER2 software, available
and also the Wise2 software, available from
The Pfam consortium
<birney at sanger.ac.uk>
More information about the Bio-soft