Clustal W, Clustal X version 1.8

Julie THOMPSON julie at titus.u-strasbg.fr
Tue Jul 6 01:26:32 EST 1999


                  Clustal W, Clustal X (Version 1.8) Release


Announcing a release of upgrades to the freely available Clustal W and X

multiple sequence alignment programs. Clustal X provides a windows
interface
(using the NCBI Vibrant toolkit) to Clustal W.

With this release, Clustal X is at last no longer beta test and we can
bring
the version numbers of Clustal X into line with Clustal W. Note the
version 1.8
programs share the same algorithms and parameterisation and produce
exactly the
same alignments.

The main changes to Clustal W are reparameterisation of the alignment
algorithm
and a number of bug fixes (listed in the README). The Gonnet PAM series
is now
the default protein matrix series and gap extension penalty has been
increased.

Clustal X has in addition received a lot of work to the windows
interface.
Users should note that screen refresh is quite slow on all compilations
of
Clustal X. In addition the Mac and PC platforms suffer from a double
refresh
during window resizing. These limitations, though annoying, do not
seriously
affect the utility of the program.

Clustal W and versions of Clustal X for PowerMac, PC (32 bit), and UNIX
(Linux, Alpha, SGI, Sun) can be downloaded from several websites
including:

       IGBMC      ftp://ftp-igbmc.u-strasbg.fr/pub/
        EBI        ftp://ftp.ebi.ac.uk/pub/software/
                   and all sites with mirrors to the EBI

Problems with the 1.8 release may be reported to any of the authors,
including:

Julie Thompson      (julie at igbmc.u-strasbg.fr)
Toby Gibson         (Toby.Gibson at EMBL-Heidelberg.de)
Des Higgins         (des at chah.ucc.ie)
Francois Jeanmougin (pingouin at igbmc.u-strasbg.fr) especially for
LINUX...


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                  POLICY ON COMMERCIAL DISTRIBUTION OF CLUSTAL W/X

Clustal W/X is freely available to the user community. However, Clustal
W/X
is increasingly being distributed as part of commercial sequence
analysis
packages. To help us safeguard future maintenance and development,
commercial
distributors of Clustal W/X must take out a NON-EXCLUSIVE LICENCE.
Anyone
wishing to commercially distribute version 1.8 of Clustal W/X should
contact the
authors unless they have previously taken out a licence.

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