No suggestions for c++ (never got a readseq in that flavor),but you can find parts of my sequence classes in java at http://iubio.bio.indiana.edu/soft/molbio/readseq/java as readseq-source.zip (see also -api- file there). - don -- -- d.gilbert--bioinformatics--indiana-u--bloomington-in-47405 -- gilbertd at bio.indiana.edu