Computing degrees of sequence conservation in multialigned sequences

Gerard Pujadas pujadas at argo.urv.es
Tue Jul 4 03:34:50 EST 2000


	Dear all,

	I'm looking for a non-commercial software for UNIX or Mac (also a
web server) that:

	1) uses a multiple sequence alignment in GCG form as input.
	2) output the degree of sequence conservation in the multialignment
in order to find (and define) in an objective way the limits of similar
sequence regions.

	In fact, I'm looking for a UNIX or Mac soft similar to the
described by Friemann & Schmitz in "A new approach for displaying
identities and differences among aligned amino acid sequences. (1992).
CABIOS 8(3):261-165."

	It would be important that the program could deal with a
multialignment with a high number of sequences (about 200) and with an
multialignment consensus length about 500.

	With many thanks in advances.

	Yours sincerely.

	Gerard.

===========================================================================
DR. GERARD PUJADAS
BIOTECNOLOGIA COMPUTACIONAL
DEPT. BIOQUIMICA I BIOTECNOLOGIA	   E-MAIL: pujadas at quimica.urv.es
UNIV. ROVIRA I VIRGILI                     PHONE: 34-977 559565
PLAÇA IMPERIAL TARRACO 1                   FAX: 34-977 559597
43005 TARRAGONA (CATALONIA)
STATE: SPAIN (EUROPEAN UNION)
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