Announcing Pfam Release 7.5

Mhairi Marshall mhairi.marshall at
Tue Aug 20 06:11:23 EST 2002

Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models.
Pfam families contain functional annotation and cross-references to
other databases.  Query sequences can be searched against the Pfam
library of profile hidden Markov models at the web sites below.

Pfam 7.5 contains 4176 families.  71% of proteins in SWISSPROT 40
and TrEMBL 18 have at least one match to a Pfam family.

For interactive access and searching see URLs


The release is also available in flat file by anonymous ftp:


The Pfam HMM library is compatible with HMMER2 software, available

and also the Wise2 software, available from


The Pfam consortium

Mhairi Marshall                        Wellcome Trust Sanger Institute, 
01223 494724                           Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK

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