SVM RNAi 3.6 for rational siRNA design

Chang Zhu czhu at changbioscience.com
Mon Apr 26 01:54:03 EST 2004


SVM RNAi 3.6 is a learning program for rational siRNA design.

For more information, please download fully functional 
trail:

http://www.changbioscience.com/download/biotoolkit.html

Comments and suggestions are welcome. Thanks.


1. Incorporates recent advances in rational siRNA 
   design.
2. Selects siRNA target sequences based on simple 
   rules.
3. Learns from past successes and failures for 
   better siRNA design. 
4. Automatically designs oligos for a variety of 
   technical platforms:
     synthetic siRNA    in vitro translated siRNA
     shRNA              vector-based siRNA
5. Tailors to user-specific systems.   
6. Eliminates unintended targets by "Blast" search
   transcribed genome sequences or predicted genes. 
7. Avoids targeting to Single Nucleotide 
   Polymorphism (SNP) sites. 
8. Generates scrambled controls.
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