Announcing Pfam 13.0

Mhairi Marshall mm1 at
Mon Apr 26 10:52:17 EST 2004

                ANNOUNCING PFAM RELEASE 13.0

Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models. Pfam
families contain functional annotation and cross-references to other
databases.  Query sequences can be searched against the Pfam library of
profile hidden Markov models at the web sites below.

Pfam 13.0 contains 7426 families.  75% of proteins in SWISSPROT 42.12
and TrEMBL 25.12 have at least one match to a Pfam family.

For interactive access and searching see URLs


The release is also available in flat file by anonymous ftp:


The Pfam HMM library is compatible with HMMER2 software, available from

and also the Wise2 software, available from


The Pfam consortium

Miss Mhairi Marshall                   Wellcome Trust Sanger Institute,
01223 494724                           Wellcome Trust Genome Campus,  Hinxton, Cambridge CB10 1SA, UK

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