Announcing Pfam 16.0

Mhairi Marshall mm1 at
Tue Nov 9 08:13:08 EST 2004

                ANNOUNCING PFAM RELEASE 16.0

Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models. Pfam
families contain functional annotation and cross-references to other
databases.  Query sequences can be searched against the Pfam library of
profile hidden Markov models at the web sites below.

Pfam 16.0 contains 7677 families.  75% of proteins in SWISSPROT 44.5
and TrEMBL 27.5 have at least one match to a Pfam family.

For interactive access and searching see URLs


The release is also available in flat file by anonymous ftp:


The Pfam HMM library is compatible with HMMER2 software, available from

and also the Wise2 software, available from


The Pfam consortium

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