[Bio-software] UniProt Release 7.0 Note

UniProt help at uniprot.org
Wed Feb 8 13:13:19 EST 2006


Dear Subscriber,


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                          UniProt Release 7.0 Note
                                 07-Feb-2006
******************************************************************************** 



CONTENTS
1. Introduction
2. Database description
3. Current release contents
4. Description of changes made to UniProt since release 6.0
5. Launch of UniProtKB Sequence/Annotation Version Database (UniSave)
6. Forthcoming changes
7. How to link to UniProt
8. Feedback
9. Acknowledgements
10. Terms of use
11. Citation
12. Contact

1. INTRODUCTION
The UniProt Consortium--European Bioinformatics Institute (EBI), Swiss 
Institute of Bioinformatics (SIB) and Protein Information Resource 
(PIR)--is pleased to announce UniProt Release 7.0 (07-Feb-2006). UniProt 
is updated bi-weekly, and can be accessed online for searches or 
download at http://www.uniprot.org.

2. DATABASE DESCRIPTION
UniProt is a centralized resource for protein sequences and functional 
information. UniProt was created by joining together the information 
from Swiss-Prot, TrEMBL and PIR. UniProt is comprised of three 
components, each optimized for different uses: a) UniProt Knowledgebase 
(UniProtKB), b) UniProt Non-redundant Reference databases (UniRef), and 
c) UniProt Archive (UniParc). Additional information on UniProt is 
available at http://www.uniprot.org/database/DBDescription.shtml and in 
the UniProt Knowledgebase user manual 
(http://expasy.org/sprot/userman.html).

3. CURRENT RELEASE CONTENTS
-------------------------------------------------------------
UniProt Release 7.0
-------------------------------------------------------------
Database -- Entries
-------------------------------------------------------------
UniProtKB -- 2,812,716 (UniProtKB/Swiss-Prot section: 207,132; 
UniProtKB/TrEMBL section: 2,605,584)
UniRef100 -- 3,085,801
UniRef90 -- 1,937,041
UniRef50 -- 994,914
UniParc -- 5,500,865
-------------------------------------------------------------
Detailed release statistics for UniProtKB/TrEMBL and 
UniProtKB/Swiss-Prot sections of the UniProt Knowledgebase can be viewed 
at http://www.ebi.ac.uk/swissprot/sptr_stats/index.html and 
http://www.expasy.org/sprot/relnotes/relstat.html, respectively.

4. DESCRIPTION OF CHANGES MADE TO UNIPROT SINCE RELEASE 6.0
UniProt Knowledgebase - To learn about the changes since the last major 
release please read the UniProtKB/Swiss-Prot and UniProtKB/TrEMBL 
release notes (http://expasy.org/sprot/relnotes/) and the recent changes 
document (http://expasy.org/sprot/relnotes/sp_news.html).

5. LAUNCH OF UNIPROTKB SEQUENCE/ANNOTATION VERSION DATABASE (UniSave)
As part of UniProt release 7, the UniProt Consortium has launched the 
UniProtKB Sequence/Annotation Version Database (UniSave), a 
comprehensive archive of UniProtKB/Swiss-Prot and UniProtKB/TrEMBL entry 
versions. Unlike the UniProt Knowledgebase which contains only the 
latest Swiss-Prot and TrEMBL entry and sequence versions, the UniProtKB 
Sequence/Annotation Version Database provides access to all versions of 
these entries to allow tracking of sequence and annotation changes.

6. FORTHCOMING CHANGES
Forthcoming changes are described in 
http://expasy.org/sprot/relnotes/sp_soon.html.

7. HOW TO LINK TO UNIPROT ENTRIES
A detailed description of how to link to UniProt entries can be found at 
http://www.uniprot.org/support/docs/linkUniProt.html

8. FEEDBACK
We are constantly trying to improve our database in terms of accuracy 
and representation and hence, consider your feedback extremely valuable. 
Please contact us if you have any questions 
(http://www.uniprot.org/support/helpdesk.shtml) or comments 
(http://www.uniprot.org/support/feedback.shtml). You can also subscribe 
to e-mail alerts (http://www.uniprot.org/support/alerts.shtml) for the 
latest information on UniProt databases.

Submit new sequence data, updates and corrections at 
http://www.uniprot.org/support/submissions.shtml

9. ACKNOWLEDGEMENTS
UniProt is supported mainly by the National Institutes of Health (NIH) 
grant U01 HG02712. Minor support for the EBI's involvement in UniProt 
comes from the European Union contracts BioBabel (QLRT-2000-00981) and 
TEMBLOR (QLRI-2001-00015) and from the NIH grant R01 HGO2273. Swiss-Prot 
activities at the SIB are supported by the Swiss Federal Government 
through the Federal Office of Education and Science. PIR activities are 
also supported by the National Science Foundation (NSF) grants 
DBI-0138188 and ITR-0205470.

10. TERMS OF USE
UniProt is available for both commercial and non-commercial use. Please 
see http://www.uniprot.org/terms for details.

11. CITATION
If you want to cite UniProt in a publication please use the following 
reference:
Wu CH, Apweiler R, Bairoch A, Natale DA, Barker WC, Boeckmann B, Ferro 
S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Mazumder R, 
O'Donovan C, Redaschi N, Suzek B.  The Universal Protein Resource 
(UniProt): an expanding universe of protein information. Nucleic Acids 
Res. 2006 Jan 1;34(Database issue):D187-91.

12. CONTACT
EMBL Outstation
European Bioinformatics Institute (EBI)
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD
United Kingdom
Telephone: (+44 1223) 494 444
Fax: (+44 1223) 494 468
Electronic mail address: datalib at ebi.ac.uk / swissprot at ebi.ac.uk
WWW server: http://www.ebi.ac.uk/

Swiss Institute of Bioinformatics (SIB)
Centre Medical Universitaire
1, rue Michel Servet
1211 Geneva 4
Switzerland
Telephone: (+41 22) 702 50 50
Fax: (+41 22) 702 58 58
Electronic mail address: swiss-prot at expasy.org
WWW server: http://www.expasy.org/

Protein Information Resource (PIR)
Georgetown University Medical Center
3300 Whitehaven Street NW
Suite 1200
Washington, DC 20007
United States of America
Telephone: (+1 202) 687 2121
Fax: (+1 202) 687 0057
Electronic mail address: pirmail at georgetown.edu
WWW server: http://pir.georgetown.edu

Sincerely,

UniProt Help Desk

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