TRANSFAC 3.4

Thomas Heinemeyer thh at GBF.DE
Wed May 20 09:44:21 EST 1998


The TRANSFAC server now has made accessible the new release 3.4 of the
TRANSFAC database (Heinemeyer et al., 1998, Nucleic Acids Res. 26:364-370):

http://transfac.gbf.de/

TRANSFAC is a database on eukaryotic transcription factors and their
binding sites. As new features, it visualizes the items of the feature list
(FACTOR table) as well as element positions within regulatory regions (GENE
table). Moreover, the data volume has increased comprising now 2376 FACTOR
and 4945  SITE entries.

The SRS 5.1.0 version on the TRANSFAC server also offers access to the
databases TRRD (Transcription Regulatory Region Database, Institute of
Cytology and Genetics [ICG], Novosibirsk, Russia; N. A. Kolchanov/A. Kel et
al.) and to COMPEL, a database on composite elements (joint effort by ICG
and GBF). Available at:

	http://transfac.gbf.de/srs5/

As many users know, the sequence information contained in the SITE table is
used by PatSearch 1.1 to interactively scan DNA sequences for potential TF
binding sites. This program is accessible at:

	http://transfac.gbf.de/cgi-bin/patSearch/patsearch.pl

An updated library of matrices for transcription factor binding sites is
provided which can be used for sequence analysis with MatInspector release
2.2 (Quandt et al., 1995, Nucleic Acids Res. 23:4878-4884). 
This tool is available at 

	http://transfac.gbf.de/cgi-bin/matSearch/matsearch.pl
or at
	http://www.gsf.de/BIODV/matinspector.html
(Thomas Werner and coworkers).

Please, forward this mail to your colleagues which may be interested in
using these tools.

On behalf of the TRANSFAC team:
Edgar Wingender
Thomas Heinemeyer

GBF - Braunschweig, May 15, 1998

------------------------------------------------------------

TRANSFAC-Team			Tel.:	+49(0)531 6181 427 
Ges. f. Biotechn. Forsch. mbH		Fax:	+49(0)531 6181 266 
Abt. Genomanalyse			E-Mail: transfac at gbf.de
Mascheroder Weg 1			http://transfac.gbf.de/
D-38124 Braunschweig





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