From sonbenitez from gmail.com Mon Jul 21 12:47:29 2008 From: sonbenitez from gmail.com (Sonic) Date: Mon Jul 21 21:35:18 2008 Subject: [Bio-www] Grid/Nano Message-ID: <821c774c-97f8-4f85-b662-d3a6e66b8dfb@d77g2000hsb.googlegroups.com> Dear All Due to I am working on a project I need some information. Any of you are working on Grid computing And/Or Nanomedicine Or Nanoinformatics? Thanks! From may from genomatix.de Tue Jul 29 08:17:22 2008 From: may from genomatix.de (Klaus May) Date: Tue Jul 29 12:35:31 2008 Subject: [Bio-www] Analysis of Next Generation Sequencing data Message-ID: <4dbed9ec-912d-41f9-8c95-1fdd0e7fd9a5@m3g2000hsc.googlegroups.com> Dear Group members, a recent Science publication: "A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome" [url]http://www.sciencemag.org/cgi/content/abstract/1160342[/url] demonstrates capabilities of two products from Genomatix [url]www.genomatix.de[/url] Genomatix delivers powerful turnkey solutions downstream of Next Generation Sequencing (NGS) devices, following the Genomatix tradition of highest scientific standards and cutting edge technology. Genomatix solutions work with data from all available NGS system providers: Illumina´s Genome Analyzer (Solexa), Roche (454), The SOLiD TM System by Applied Biosystems, and HeliScope by Helicos. Genomatix Mapping Station (GMS) delivers ultra-fast mapping of sequence reads of any length above 9 base pairs. Ten million typical NGS reads of variable lengths are perfectly and uniquely mapped to the human genome in less than 30 minutes. GMS is flexible and allows for any number of indels and point mutations, delivering an uniqueness measure for each mapped read. It takes the NGS system internal error checking into account and detects new SNPs. Cutting edge technology identifies splice junction tags for advanced transcriptome analysis. Genomatix Genome Analyzer (GGA) is the complete solution for ChIP-seq and transcriptome analysis downstream of mapping the NGS system reads to the genome with the Genomatix Mapping Station, or any other technology. Terabytes of annotation data complement the results from the NGS experiment and expand by optional integration with each new sequencing run to a customized genome database. Easy-to-use visualization and genome wide correlations allow for meta-analysis of all kind of data-sets. Integrated comparative genomics procedures allow for phylogenetical conservation analysis of findings. Genome wide transcription factor analysis, gene regulatory region analysis, regulatory SNPs, epigenetic modification analysis, DNase- seq, digital gene expression with normalization and quantification of expression values… all required data and hardware in one technology unit at your lab. GGA is operated through a comprehensive easy-to-use web based interface for the biologist, plus features full data structure access and command line driven procedures for the bio- informatician for easy integration into own high-throughput pipelines.