Diff. between female and male chromosomes?
roger at kean.ucs.mun.ca
Fri Mar 25 10:44:20 EST 1994
In article <sjj.32.0008A309 at srcros1.pathology.ufl.edu>, sjj at srcros1.pathology.ufl.edu (Song-Muh Jong) writes:
> I used to have an impression that human chromosomes are the simple 23 pairs.
> However, the linkage maps of human chromosomes indicate that female maps are
> larger than male maps. Can someone explain this phenomenon?
> Song-Muh Jong TEL: (904) 392-0011
This is simply a consequence of the fact that during meiosis in a
female (i.e. ovum production), the rate of recombination (crossing over)
between homologous pairs of chromosomes is greater than the rate during
meiosis in a male (during spermatogenesis).
In linkage maps, map distance is a function of the rate of
recombination between loci on the map. Thus female map distances are
Roger C. Green, Faculty of Medicine Phone: (709)737-6884
Memorial University , St. John's, Newfoundland FAX : (709)737-7010
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