Genome Map

Keith Robison robison at lipid.harvard.edu
Mon Apr 24 21:41:01 EST 1995


Justin2401 (justin2401 at aol.com) wrote:
: Any one know where (internet address, etc...) I could get a fairly up to
: date map of the human genome?

You might start with URL's contained at the following two URLs:

http://www-bprc.mps.ohio-state.edu/cgi-bin/hpp?genetics.html
http://golgi.harvard.edu/htbin/biopages?genome|chromosome|map

will list a lot of genome-related (not all human!) sites, many of
which have maps.  

One "problem" with human genome maps is that there are many different
types of maps, based on different techniques.  For example, 
a physical map shows the location of DNA fragments or DNA landmarks,
whereas a recombinational map shows the observed degree of 
genetic linkage between markers (which also differs somewhat
by which parent the chromosome is inherited from).  And, of course,
these are both broad categories which encompass different techniques.
As you might guess, one challenge of genomics is figuring out ways
to either experimentally or computationally merge maps developed with
different techniques or in different experiments.  There are a number
of sites at the above URL's which present integrated maps or 
give you access to experimental map integrators.

Enjoy!!!

Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison at mito.harvard.edu 






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