CSH Genome Sequencing Course

Rick Wilson rwilson at WATSON.WUSTL.EDU
Fri Jan 13 17:00:28 EST 1995

Cold Spring Harbor Laboratory


Correspondence should be addressed to:
Cold Spring Harbor Laboratory
The Meetings Office
1 Bungtown Road, P.O. Box 100
Cold Spring Harbor
New York 11724-2213

Phone: (meetings)    516 367 8346
	   (courses)   516 367 8345
Fax:		         516 367 8845
E-mail: meetings at cshl.org
World wide web site at http://www.cshl.org/

1) Introduction
2) Full description of course (dates, instructors, description, application deadline) 
3) Short list of meetings and courses
4) Information for course applicants
5) 1995 course price
6) Sponsors of the 1994 Courses Program
7) Getting to Cold Spring Harbor Laboratory
8) General information about Cold Spring Harbor Laboratory

Application forms and further information can be obtained from the above address.

1) Introduction

Cold Spring Harbor Laboratory is a non-profit independent research and educational institution chartered by the University of the State of New York. The Laboratory employs 550 people, including a research staff of almost 200 Ph.D. scientists and 50 graduate students. Cold Spring Harbor Laboratory's primary goal is to carry out first-rate scientific research. However, the Laboratory pursues other goals which we believe are vital to the well-being of science and scientists: scientific communication; training scientists; public education; and publishing. The Laboratory is located thirty-five miles east of New York City on the scenic north shore of Long Island.

Each year, over 5,000 scientists worldwide attend one or several of the more than 15 scientific meetings held at Cold Spring Harbor Laboratory in the award- winning Grace Auditorium. The flagship of this program is the annual Symposium on Quantitative Biology, one of the most prestigious meetings in molecular biology. Professional meetings are an integral part of a scientist's job; they are a primary means by which scientists stay current on the latest results and techniques in their field.

Complementing our meetings program is our annual program of 25 high-level courses. Directed primarily at post-doctoral level scientists, these intensive courses allow practicing researchers to immerse themselves in new techniques and ideas that they can apply immediately to their own research. Many of these courses are laboratory courses held in our Beckman Neuroscience Center, which was completed in 1991. For more than 50 years, courses at Cold Spring Harbor have trained the rising stars in emerging disciplines and shaped the direction of research, both at Cold Spring Harbor and elsewhere.

2) Full Description of Course

Application Deadline January 31, 1995

ADVANCED GENOME SEQUENCE ANALYSIS                         March 14 - 27, 1995

Ellson Y. Chen, Perkin Elmer Corporation
Richard Gibbs, Baylor College of Medicine
W. Richard McCombie, Cold Spring Harbor Laboratory
Richard K. Wilson, Washington University

Recent advances in the automation of DNA sequencing have opened new possibilities for the analysis of complex genomes at the DNA sequence level.  This two week course will provide intensive training in this rapidly evolving field.  The course will emphasize techniques and strategies for using automated sequencers to sequence large, contiguous genomic regions.  Students will carry out all of the steps in the sequencing process from preparing cosmid DNA to computer analysis of the finished sequence.  Topics will include subclone library generation, large-scale template purification, sequencing reactions, gel analysis on automated sequencers, sequence assembly, gap filling and conflict resolution.  Students will work in groups to sequence a large region of DNA and through this process be trained in crucial project and data management techniques. A series of lecturers will discuss their applications of these techniques as well as alternate strategies for high speed automated DNA!

3) Short list of 1995 meetings and courses

1995 Meetings (in chronological order)

Molecular and Behavioral Biology of Aplysia and Related Molluscs
The Cytoskeleton & Cell Function
Tyrosine Phosphorylation & Cell Signalling
Genome Mapping & Sequencing
RNA Processing
Symposium: Protein Kinesis - The Dynamics of Protein Trafficking & Stability
Yeast Cell Biology
Molecular Genetics of Bacteria & Phages
Cancer Cells: Mechanisms of 
Eukaryotic Transcription
Eukaryotic DNA Replication
Molecular Approaches to the Control of Infectious Diseases
Programmed Cell Death
Plant Signalling in Development
Neurobiology of Drosophila

1995 Courses  (in alphabetical order) 

Advanced Bacterial Genetics
Advanced Genome Sequence Analysis
Advanced In Situ Hybridization & Immunocytochemistry
Advanced Molecular Cloning & Expression of Eukaryotic Genes
Arabidopsis Molecular Genetics
Cloning and Analysis of Large DNA Molecules
Computational Genomics
Early Development of Xenopus Laevis
Macromolecular Crystallography
Molecular Embryology of the Mouse
Molecular Markers for Plant Breeding & Plant Genetics
Phage Display of Combinatorial Antibodies
Protein Purification & Characterization
YACs in Structural and Biological Genome Analysis
Yeast Genetics

Courses in Neurobiology

Brain Mapping
Developmental Neurobiology
Imaging Structure and Function in the Nervous System
Molecular Approaches to Ion Channel and Function
Molecular Cloning of Neural Genes
Neurobiology of Drosophila 
Neurobiology of Human Neurological Disease: Mechanisms of Human Neurodegeneration
Structure, Function & Development of the Visual System
The Biology of Memory: From Molecules to Behavior 

4) Information for Course Applicants

Mail the application form plus 3 additional copies of application and accompanying material to the Course Registrar on or before the course deadline. If applying for more than one course, a separate application form plus 3 additional copies must be submitted for each course.  Please select one course per session.

Selection Process:
Each year, the instructors are confronted with the difficult task of selecting the students for our courses from a large number of well-qualified applicants.  To facilitate the application process, students are asked to provide information documenting their request for a place in the course.  First and foremost, applicants should give their reasons for wanting to take the course.   As part of this, you should briefly outline your career.  It is highly recommended that you supplement your application with one or more letters of recommendation.  Applicants should remember that selection is based upon the degree to which they would benefit from this training opportunity; this in turn will be judged from the information given by the applicants.

Applicants will be notified by mail whether or not they have been accepted to attend.  The decisions often take several weeks after the application deadline to be finalized and announced.


Scholarship support is available to all qualified applicants based on need.  Any candidate requesting financial assistance MUST request it when submitting the application.  Attach a separate letter stating the amount requested and give a full justification for the required support.  The amount awarded will be based upon the availability of funding.

All students must live in the Laboratory dormitories and take meals in the dining room.  Most of the rooms are multiple occupancy and/or shared bath.  Please be sure to indicate gender on the application form.  Due to space limitations, families cannot be housed on grounds; there are no exceptions to this policy!

Course Application Checklist:
Mail original plus 3 copies of the following:
** Original application for each course applied for.					
** Letter and/or curriculum vitae outlining your career including reasons why taking the course would benefit you				
** Letter(s) of recommendation				
**(Stipend request)				

5) Prices  for 1995 Courses:
Length of Course		   Cost *

6 Days				$1,155.00
1 Week				$1,215.00
10 Days			$1,460.00
2 Weeks			$1,720.00 <= COST OF THIS COURSE
3 Weeks			$2,180.00

* Cost includes tuition, food and housing

6) Sponsors of the 1994 Courses Program (not specifically for this course)

The Howard Hughes Medical Institute   **  The Esther A. & Joseph Klingenstein Fund, Inc. **  United States Department of Agriculture ** United States Department of Energy   ** National Cancer Institute ** National Center of Human Genome Research ** National Institute of General Medical Sciences ** National Institute of Mental Health ** National Institutes of Health ** National Science Foundation 

7) Getting to Cold Spring Harbor Laboratory 

** New York Airports: J.F. Kennedy, La Guardia and L.I. MacArthur Airports are most convenient to the Laboratory (allow 1 1/2 - 2 hours travel time each way). Cold Spring Harbor Laboratory does not coordinate travel arrangements from local airports.  
** Limousines:  Prices for JFK and LaGuardia only!
Syosset Limousine - 516-364-9681, reservation required. Private Car (1 - 9 people).  Cost = $65.00 for 1 person, $33.00 pp. for 2, $25.00 pp. for 3 or more.
Classic Limousine - 516-567-5100 (or 1-800-666-4949 outside New York). Shared Ride Service (possible stops at other terminals/destinations).  Use courtesy phone at airport.  No reservation required.  Cost = $33.00 per person. 
Other transportation options are available at the airports. Do not use taxicabs for transportation from  the airport to CSHL. 
**    Railroad: Long Island Railroad is located in Penn Station. Take the PT JEFFERSON BRANCH train to SYOSSET.  Note: Possible transfer at Jamaica Station.  Taxis usually meet arriving trains at Syosset station ticket office. Syosset Taxi 921-2141; $6.50 for 1 person, $4.00 each additional person.
** Automobile: From the Long Island Expressway (Rte 495), 
Exit 41 North (Route 106-107). On 106-107, bear right at fork (Route 106 - Oyster Bay).  Travel 3.5 miles on Rte 106, make a right turn (East) onto Route 25A (town of East Norwich).  Travel 4 miles. The lab entrance is on the left.  (A gold Victorian house marks the entrance).
** New York - Connecticut Ferry Services:
Port Jefferson - Bridgeport (516-473-0286)
Orient Point - New London (516-323-2743)

8) General Information  about services at Cold Spring Harbor Laboratory

** Registration: Please register at Grace Auditorium upon your arrival at the laboratory. Meetings begin at 7:30 in the evening. Dinner is served from 5:30 to 7:30 prior to meetings.  Please call ahead if you plan to arrive at the lab after midnight.
** Parking: All vehicles MUST receive a Temporary Parking Permit from The Meetings Office.  Any vehicle on grounds without such a permit will be subject to booting or towing.
** Phones / Faxes: Participants can receive faxes at the Meetings Office (516) 367-8845. Payphones and house phones are located throughout the campus.
Bookstore: The Bookstore is located in the lower level of Grace Auditorium. Store hours are posted.
** Computer Facilities: Lower level of Grace Auditorium, equipped with PC, Mac & laser printer.  To access your e-mail, you must know the name of your home server.

Correspondence should be addressed to:

Cold Spring Harbor Laboratory
The Meetings Office
1 Bungtown Road, P.O. Box 100
Cold Spring Harbor
New York 11724-2213

Phone: (meetings) 516 367 8346
	(courses)   516 367 8345
Fax:		      516 367 8845
E-mail: meetings at cshl.org
World wide web site at http://www.cshl.org/

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