Gene within a gene

Keith Robison robison at nucleus.harvard.edu
Tue May 23 21:46:10 EST 1995

Dan Wells (DWELLS at UH.EDU) wrote:
: I remember reading of a mammalian gene that was contained 
: within the intron of another gene, but I cant remember which
: genes were involved. Can some one help me out.

There are several of examples of these -- but I can't claim
to list them all.  The neurofibromatosis type I gene
contains at least one other gene in its introns, and
I think it's more like 2 or 3.  The DNA sequence for this
gene is a member of the still-exclusive 100Kb Club, whose
membership list is at


You'll find a link there to the Entrez data for this sequence,
which will in turn let you get to the citations.

My guess is that many large (>50Kb) introns will contain
additional transcription units.


Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison at mito.harvard.edu 

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