music & DNA

David A. Adler dadler at u.washington.edu
Thu Sep 7 14:42:46 EST 1995


In article <42n77d$1d6g at serra.unipi.it> vassallo at cli.di.unipi.it (Fabrizio  
Vassallo) writes:
> Hallo!
> Have anyone heard of relations betw. music & DNA?
> please post me
> 
> Fabrizio

Susumo Ohno has done some work on representing DNA/protein sequences as
musical notes - as a start see for example:

Author:        Ohno-S.
Title:         A song in praise of peptide palindromes.
Source:        Leukemia.  1993 Aug.  7 Suppl 2.  P S157-9.
Journal Title: LEUKEMIA.
Abstract:      Peptide palindromes are invariably found in all proteins,  
and
               long palindromes exceeding 10 residues in length are not  
rare.
               They are particularly abundant in DNA-binding proteins
               such as H1 histone. When a complementary strand of the  
coding
               sequence is translatable being free of a chain terminator,  
a
               complementary protein encode by it becomes equally abundant  
in
               peptide palindromes. The simultaneous musical  
transformation of
               both strands of mouse H1 histone variety-1 DNA enable us
               to appreciate the symmetrical beauty of successive  
palindromes
               appearing in both H1 histone and its complementary protein.

Hope this helps,
David
--
David A. Adler                  Pathology, Box 357470
University of Washington        Seattle, WA 98195
(206) 543-0716 (phone)		(206) 543-3644 (fax)
"Science is nothing but trained and organized common sense"
T.H.Huxley




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