Its Slime Time...

Robert Preston rapr at med.pitt.edu
Sun Jan 19 14:40:52 EST 1997

In article <2df8d690 at rohmhaas.com>, Kenneth_M_Wiencek at ROHMHAAS.COM
(Kenneth M Wiencek) wrote:

>      Here's a question to ponder...
>      What is a biofilm anyway?  Is one attached cell a biofilm? 100? 
>      1000000?  A monolayer?  Is a 3-D structure a requirement for a 
>      "biofilm"?  .....[edit]....if the characteristics of cells change 
>      immediately upon attachment (a physiological response to being 
>      attached such as increased resistance to antimicrobials), then perhaps 
>      a biofilm could be one attached cell ("a biofilm onto itself")

It seems to me that combining one attached cell with the exponential growth
equation necessarily implies the presence of a large multicell film after not
very many generations (or one dead attached cell if the growth rate constant
is negative).  Single cells are irrelevant except as progenitors for

rapr at med.pitt.edu

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