conference on computational biology

Joachim Frank JOACHIM at TETHYS.PH.ALBANY.EDU
Mon Jul 9 15:31:00 EST 1990


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              ANNOUNCEMENT OF YOUNG INVESTIGATOR SUPPORT
 
                FOR ATTENDING THE ALBANY CONFERENCE ON                 

            "CONVERGING APPROACHES IN COMPUTATIONAL BIOLOGY"	
      
                        SEPTEMBER, 13-16, 1990

                          RENSSELAERVILLE, NY

      
     To encourage participation of new investigators in this meeting, a 
limited number of registration waivers and travel grants will be awarded
to graduate students, as well as to other young investigators (postdoctoral 
students, junior faculty) in the area of Computational Biology.  

     Anyone interested in receiving such an award should submit a
registration form (available on request) along with a brief letter explaining
his/her research interests. Graduate students should also include a letter of
recommendation from a faculty advisor.  If applications exceed available
funds, selection will be by lottery, with priority given to those presenting
posters at the meeting.  Applications from women and minorities are 
encouraged.

     For registration forms, please contact the conference coordinator,
Carole Keith, 518-442-4327, FAX 518-442-4767, or write to The 1990 Albany
Conference, P.O. Box 8836, Albany, NY 12208-0836. 

     Further information about this meeting may also be obtained by calling 
one of the conference organizers: 
   
                         Steven Bryant 518-473-3382
                      Jacquelyn Fetrow 518-442-4389
                         Joachim Frank 518-474-7002
                      Charles Lawrence 518-473-3382  
                       Carmen Mannella 518-474-2462
                            David Shub 518-442-4324 

     APPLICATION DEADLINE: July 30, 1990.

     A description of the meeting follows this announcement.


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                     CONFERENCE ANNOUNCEMENT (revised) 

             "CONVERGING APPROACHES IN COMPUTATIONAL BIOLOGY"	

                         SEPTEMBER, 13-16, 1990

                           RENSSELAERVILLE, NY
		


     An interdisciplinary meeting on "Converging Approaches in Computational
Biology" will be held September 13-16, 1990 in Rensselaerville near Albany,
New York, under the auspices of the Center for Molecular Genetics of the
State University of New York at Albany.  The concept of the meeting reflects
an increased awareness within the scientific community that computational
tools being developed in diverse fields have common elements or close
analogies. The aim of the conference is to identify these elements and to
facilitate an exchange among computational biologists that is not normally
possible within the constraints of topical, single-discipline meetings. 

     The meeting will bring together about 100 scientists working in a wide
range of disciplines (such as x-ray crystallography, electron microscopy,
sequence analysis, neurophysiological signal processing) with the purpose of
encouraging interdisciplinary exchange on underlying concepts of mathematical
modeling and techniques of numerical analyses in biology.  To this end, the
meeting is organized into sessions according to particular mathematical or
computational themes: Latent Feature Identification, Information Theoretical
Approaches, Methods for Reconstruction and Refinement, Simulations and
Modelling, Discovery of Patterns. 


CONFERENCE SITE

     The conference, one of the Albany Conference series held annually since
1984, will take place at the Rennselaerville Conference Center, located 30
miles southwest of Albany, NY in the Helderberg Mountains.  The Institute
offers on-campus facilities including a large auditorium with all necessary
audio-visual equipment, and smaller conference halls for informal workshops
and poster sessions.  The Weathervane Restaurant, located on-campus and
formerly the carriage house of the Huyck estate, provides meals and
refreshments, while overnight lodging is available in the modern and classic
estate houses. Rooms are assigned in advance to registrants, and
transportation to and from Rensselaerville is provided from the airport, as
well as train and bus stations.  The rural, secluded setting of the
conference, the limited number of participants and the scheduling of sessions
in the morning and the evening -- leaving the afternoons free -- are intended
to facilitate informal discussions among conference participants. 


CONFERENCE FORMAT

     The conference will consist of three morning and two evening sessions
over a period of three nights and days (Thursday evening through Sunday
morning).  Each session will be devoted to a particular computational theme 
and will be comprised of four or five 30-minute talks by experts from
different biological disciplines (with strong representation from structural
biology), interspersed by question-and-answer periods of 15-20 minutes. 
There will be an open-ended discussion period at the end of each session,
with the speakers and chair serving as a panel. 


CONFERENCE PROGRAM 

     The following is a summary (as of July 1) of the sessions planned for
the meeting on Computational Biology.  

SESSION 1. METHODS FOR RECONSTRUCTION AND REFINEMENT 

Chair: Dr. Mario Amzel, Johns Hopkins University

Speakers:		

Dr. Sarah J. Nelson       Fox Chase Cancer Center
Peaks, patterns and protein structures from high resolution NMR spectra

Dr. A.B. Goncharov        Academy of Sciences, USSR
Determination of angles among randomly oriented particles of unknown structure

Dr. Lynn Ten Eyck         General Atomics			 
Image reconstruction and model refinement in protein crystallography

Dr. John Kuriyan          Rockefeller University
Application of molecular dynamics to crystallographic refinement of
proteins


SESSION 2. INFORMATION THEORETICAL APPROACHES 

Chair: Dr. Andrew McLachlan, Medical Research Council, Cambridge

Speakers:

Dr.  Joel Trussel         North Carolina State Univ.
Set theoretic approaches to estimation and identification
	 	
Dr. Michael Unser         National Institutes of Health
Optimum resolution conversion and scale-space representation of images

Dr. Bi-Cheng Wang         Univ. of Pittsburgh
Resolution of phase ambiguity in macromolecular crystallography by a 
noise filtering process

Dr. Temple F. Smith       Dana Farber Cancer Inst.
Identification of functional pattern correlates


SESSION 3. LATENT STRUCTURE IDENTIFICATION

Chair: Dr. Fred E. Cohen, Univ. of California, San Francisco

Speakers:		

Dr. Patrick Argos         European Molecular Biology Laboratory
Comparing protein sequences, sensitive methods and realistic 
evaluations	

Dr. Piotr J. Franaszczuk  University of Maryland
Direction of postsynaptic potentials in intracellular recordings
from neurons in tissue culture

Dr. Joachim Frank         Wadsworth Center, NYS Health Dept.
Classifying noisy projections of an unknown structure

Dr. Charles E. Lawrence   Wadsworth Center, NYS Health Dept.
Analysis of misaligned data with application to sequence analysis 
and neurophysiology

Dr. Gary D. Stormo        Univ. of Colorado
Identifying functional domains in biological sequences

       
SESSION 4. SIMULATIONS AND MODELLING

Speakers:	

Dr. Ken A. Dill           Univ. California, San Francisco
Statistical mechanics of protein folding

Dr. Jeffrey Skolnick      Scripps Research Inst.
Models of globular protein folding

Dr. Richard J. Feldmann   National Institutes of Health
Could we ever design a biology?

Dr. Kathleen A. Palmer    Cornell University
Modelling "loops" of proteins: homology and energy-based methods
and applications


SESSION 5. DISCOVERY OF PATTERNS

Speakers:	

Dr. Alan S. Lapedes       Los Alamos National Laboratory
Neural nets, optimization and statistics: a biological case study

Dr. Michael N. Liebman    Amoco Technology Co.   
Application of neural networks to structure-function analysis in
proteins

Dr. Andrew D. McLachlan   Medical Research Council, Cambridge
Periodic structural patterns in proteins


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REGISTRATION  INFORMATION

CONFERENCE FEE: $450 includes registration, accomodations (double occupancy), 
meals and transportation between the conference center and Albany airport.  A 
limited number of single occupancy accomodations are available for an extra 
$100.  Payment of the full fee will be required by AUGUST 23, 1990.  Please 
note that neither the Albany Conferences nor the Rensselaerville Conference 
Center accepts credit cards.

APPLICATION DEADLINE: July 30, 1990.  

For further information and a copy of the application form for the 1990 
Albany Conference on "Converging Techniques in Computational Biology", please 
call the conference coordinator, Carole Keith, 518-442-4327, FAX 
518-442-4767, or write to The 1990 Albany Conference, P.O. Box 8836, Albany, 
NY 12208-0836.


 



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