paba dmae cancer

Stephen L. Rogers slrg3016 at uxa.cso.uiuc.edu
Sat Apr 18 17:33:31 EST 1992


allens at yang.earlham.edu (Allen Smith) writes:

>In article <31544 at sdcc12.ucsd.edu>, jtucker at sdcc13.ucsd.edu (Joe T. Ucker       ) writes:
>> 
>>   
>> 	I've received a few letters and have seen a brief discussion
>> 	without any sort of resolution on the rumour I posted sbout
>> 	DMAE, it's solvent and cancer.  A reader contacted twinlabs
>> 	(tm) and stated the nervous operator shakily confirmed that
>> 	the only solvent that they used with their DMAE was water.
>> 
>> 	I recently found a DMAE bottle in a healthfood store and
>> 	found the DMAE in TWinlabs to be in  a PABA (para-amino ben-
>> 	zoic acid) base.  The solvent is indeed water.  
>> 
>> 	So I checked out the biomed libraries' reports on PABA.  I
>> 	found a few reports of similar substances being
>> 	carcinogenic.  I'm an amateur and I don't have these
>> 	articles handy, but I believe these were pyrridines.  I
>> 	found Peter Alex the med student on the shuttle today and
>> 	he suggested the benzoic acid was the problem.  He 
>> 	said that it is hypothesized that benzene itself is the
>> 	culprit in causing cancer.  We talked a little about the
>> 	chemical structure and the floating electrons of the 
>> 	benzene ring and the efficacy of this structure in fucking
>> 	with DNA replication.  Benzene is the same thing responsible
>> 	for the potent carcinogenic activities of burnt barbeque
>> 	meterial which is basically just a clump of benzene riings.
>> 	
>> 	The journals were mostly unreadable to this novice but 
>> 	by the availability of benzocaine, sunscreens containing
>> 	benzene-type chemicals (which react with UV light to create
>> 	free raqdicals) that this issue is either unresolved or
>> 	not yet critical (as the journals seemed to suggest- in-
>> 	conclusive.)  PATMS (peter alex the med student) believed
>> 	the necessity of these products in medical practices
>>         currently outweighs their dangers.  This didn't make sense
>> 	to me, aS the use in suncreen is to PREVENT cancer while
>> 	he claimed these same substances CAUSED cancer.
>> 
>> 	Maybe this shouldn't be taken all that seriously.  But
>> 	I'm sure a few others as well as myself would appreciate
>> 	it if a more biochemically-minded reader could make sense
>> 	of this and give a few words to the newsgroups.
>> 
>	Although I'm familiar with that benzene is linked to cancer, I 
>can't  find any references immediately available which say anything more 
>than that. I've cross-posted this to a few other newsgroups whose readers 
>may be able to help.
I
The fact that a given compound possesses a benzene-ring structure does not
necessarily imply that a substance is linked to carcinogenesis.  Three of the
twenty amino acids that serve as the basic building blocks for proteins,
tryptophane, phenylalanine, and tyrosine, contain aromatic side chains.



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