paba dmae cancer
Stephen L. Rogers
slrg3016 at uxa.cso.uiuc.edu
Sat Apr 18 17:33:31 EST 1992
allens at yang.earlham.edu (Allen Smith) writes:
>In article <31544 at sdcc12.ucsd.edu>, jtucker at sdcc13.ucsd.edu (Joe T. Ucker ) writes:
>> I've received a few letters and have seen a brief discussion
>> without any sort of resolution on the rumour I posted sbout
>> DMAE, it's solvent and cancer. A reader contacted twinlabs
>> (tm) and stated the nervous operator shakily confirmed that
>> the only solvent that they used with their DMAE was water.
>> I recently found a DMAE bottle in a healthfood store and
>> found the DMAE in TWinlabs to be in a PABA (para-amino ben-
>> zoic acid) base. The solvent is indeed water.
>> So I checked out the biomed libraries' reports on PABA. I
>> found a few reports of similar substances being
>> carcinogenic. I'm an amateur and I don't have these
>> articles handy, but I believe these were pyrridines. I
>> found Peter Alex the med student on the shuttle today and
>> he suggested the benzoic acid was the problem. He
>> said that it is hypothesized that benzene itself is the
>> culprit in causing cancer. We talked a little about the
>> chemical structure and the floating electrons of the
>> benzene ring and the efficacy of this structure in fucking
>> with DNA replication. Benzene is the same thing responsible
>> for the potent carcinogenic activities of burnt barbeque
>> meterial which is basically just a clump of benzene riings.
>> The journals were mostly unreadable to this novice but
>> by the availability of benzocaine, sunscreens containing
>> benzene-type chemicals (which react with UV light to create
>> free raqdicals) that this issue is either unresolved or
>> not yet critical (as the journals seemed to suggest- in-
>> conclusive.) PATMS (peter alex the med student) believed
>> the necessity of these products in medical practices
>> currently outweighs their dangers. This didn't make sense
>> to me, aS the use in suncreen is to PREVENT cancer while
>> he claimed these same substances CAUSED cancer.
>> Maybe this shouldn't be taken all that seriously. But
>> I'm sure a few others as well as myself would appreciate
>> it if a more biochemically-minded reader could make sense
>> of this and give a few words to the newsgroups.
> Although I'm familiar with that benzene is linked to cancer, I
>can't find any references immediately available which say anything more
>than that. I've cross-posted this to a few other newsgroups whose readers
>may be able to help.
The fact that a given compound possesses a benzene-ring structure does not
necessarily imply that a substance is linked to carcinogenesis. Three of the
twenty amino acids that serve as the basic building blocks for proteins,
tryptophane, phenylalanine, and tyrosine, contain aromatic side chains.
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