Amphetamine and Metabolism
B. Jonathan Bieley
bieley at Reed.Edu
Sat Apr 17 01:25:42 EST 1993
I am looking to scale an amphetamine dosage from the literature from mice
to rats. So, I am looking for references in two related areas:
- the effect basal metabolic rate, and changes in metabolc rate,
have on the pharmacology of amphetamine, i.e. do I really
have to care about this or am I being overly cautious?
This would probably be within subjects but across
task condition, such as resting versus running, or
this would be intraspecific relationships based on
basal metabolic rate.
- the differences in basal metabolic rate between mice and rats.
Specifically I need to get some idea of the interspecific
scalling of basal metabolic rate so that if I can scale
the dosage accordingly.
Department of Psychology
bieley at reed.edu
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