What is locus?

Keith Robison robison1 at husc10.harvard.edu
Wed Mar 17 11:50:55 EST 1993

I am forwarding this to the bionet groups in hopes that it will
generate some interesting discussion.  Follow-ups should show
up in sci.bio.

Keith R.  robison at biosun.harvard.edu

In article <1993Mar17.105245.22056 at reks.uia.ac.be> Przemko Tylzanowski writes:
>Hi netters!
>I would like to ask this question about locus. It came up during one of lab discussions and we could not resolv it. Here it goes: What is the definition of a locus? Is it a functional one (collagen locus etc) or is it positional one (as in case of RFLPs that may identify a locus). In the former case one could not talk about gene locus if the function of that gene is unknown. One could just talk about its position on the chromosome, with respect to other genes etc.
>In the latter case, in principle, even a single base could be defining a locus.
>Various textbooks are most unhelpful in our quest for the answer.
>So... Anyone out there???
>ThanX a lot

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