robison1 at husc10.harvard.edu
Fri Oct 29 09:02:11 EST 1993
LEES at SASK.USASK.CA writes:
>Is introns of prokaryotes really intron like those of eukaryotes?
>Are they between coding region and spliced before translation into
All known prokaryotic introns are self-splicing -- hence they
appear to be very different from eukaryotic nuclear introns
(which require a complex spliceosomal apparatus) but similar
to organellar introns.
Most introns in prokaryotes are in tRNA genes; however I believe the
T4 phage intron is in a protein-coding regions as well as the recently
described group II introns (the Nature reference is floating around
Reviews on the subject are not difficult to come by -- there was a
News & Views accompanying the recent Nature paper, and Belfort has
A smattering of cases of segments which splice _after_ translation
(i.e. self-splicing intervening protein segments) have been identified
in bacteria. A review just appeared in the October issue of BioEssays.
Department of Cellular and Developmental Biology
Department of Genetics / HHMI
robison at biosun.harvard.edu
More information about the Bioforum