BIOLOGY as ARCHITECTURE

Ari Dov Seligmann res at RUF.RICE.EDU
Fri Sep 17 17:48:10 EST 1993


I am a student of architecture at Rice University.  For my studio project I am
exploring leading edge research in Biology, namely in genetics and the possibilty of
its relation to space making in architecture. After speaking to a geneticist here at
Rice I was struck by the spatial implications of the terms and ideas surrounding these
biological concepts.

where we are looking in architecture: genetics as a model
amino acid sequence determined by DNA becomes folded protein structure--
SELF ASSEMBLY MODEL told us the amino acid sequence was the only governing
factor in determining the structure of the fold LIMITED MODEL ONLY
new factors, CHAPERONINS, bind to protein, cause alteration of structure, catalysts
in formation of folded structure---30 different proteins as chaperonins
Proteins form a structure--cell is made of proteins-- how do they arrange themselves
into a cell? Searching for more mechanisms by which constituents of cell locate
themselves in correct relationship to each other and within cell
Signals/extra amino acids attached to sequence direct proteins to particular sites in
the cell
How does cell locate itself within the body? or how do cells at particular locales in
the body differentiate into specific functions-supercellular organization of the body
Does this relate to how we are located within the city? Can a biological model lead
us to spatial forms and the plan of the city?

Any and all responses welcomed at res at es.rice.edu



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