Question on XY stuff, please help?
robison1 at husc9.harvard.edu
Sun Apr 24 19:48:48 EST 1994
gcamp1 at cc.swarthmore.edu (Geoff Camp) writes:
>Hello bio people,
>I'm sorry if this is not the exact place for this question, but I was
>wondering if someone could answer a simple question...
>I was talking with a group of people about people whose XY chromosomes are
>"screwy," like XXY, etc, and someone recalled hearing about men who were
>for some reason EXTRA-masculine. That is to say, they were very hairy and
>extremely aggressive, very MALE. We wondered if it were in ANY way
>possible to get an set of chromosomes that were XYY, or how genetically
>this could happen. Could someone be XYY, or maybe just Y ? Thanks in
>advance to anyone who answers!
XYY males exist. The most obvious explanation is meiotic non-disjunction
in the father. Studies were published which purported to show a link
between XYY and aggressiveness & criminal behaviour; it is generally
regarded that these studies were poorly conducted and used biased samples.
Most genetics textbooks cover this subject. Griffiths et al
"An Introduction to Genetic Analysis" is good; a human genetics textbook
might be even better.
Y only is impossible -- many essential genes reside on the X (otherwise,
dosage compensation via Barr bodies would be unnecessary).
Department of Cellular and Developmental Biology
Department of Genetics / HHMI
krobison at nucleus.harvard.edu
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