inquiry: base-pair stability constants

user at user at
Mon Aug 15 09:44:03 EST 1994

In article <ehom1-100894105558 at>,
ehom1 at (Erik Forbes Y. Hom) wrote:

> Does anyone know if someone followed up in determining base-pair stability
> constants in an aqueous environment - I have a paper: Kyogoku, Y. , et al.
> (1969) Biochim Biophys Acta 179:10-17 that determined these constants but
> in a deuterochloroform solvent system - which I don't think is entirely
> biologically practical.  If someone could give me some references of this
> sort, I would be exceedingly grateful.  (Are there any nucleic acid
> specialists out there?).
> Thanks in advanced,
> erik

for RNA base pairing constants, check out Turner, Sugimoto and Freier
(1988) Ann. Rev. Biophys. Biophys. Chem. 17, 167-192. It might contain
references to DNA, if that's what you're after.


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