White muscle disease in cattle
gwmartin at husc7.harvard.edu
Thu Apr 13 08:45:32 EST 1995
Eric R. Hugo (e_hugo at dsu1.dsu.nodak.edu) wrote:
: Dear Bionetters,
: A student of mine approached me with a question concerning
: a strange problem she and her husband are having on their cattle ranch.
: It seems that one cow in particular has given birth to three calves in three
: separate pregancies that exhibit symptoms similar to those descibed for white
: muscle disease. The info I have been able to dig up on this topic indicates
: that white muscle disease is caused by either a selenium or tocopherol
: deficiency. It seems rather strange to me that only 1 calf out of >250 live
: births has been exhibiting these symptoms and all three incidences have
: occurred with the same cow. Does anyone know of any bovine genetic disorder
: that would produce similar symptoms? (ataxia/limb paralysis). Or does anyone
: have any pointers to resources on the net (I've checked as many WWW sites asI
: could find). Any help would be greatly appreciated. Thanks!
One genetic cause I can think of, and I don't know that much about it, is
a defect in the selenoprotein W gene. Or if there are symptoms
indicating defects in thyroid hormone levels/metabolism, there may be a
mutation in a gene responsible for selnium metabolism or the translation
of selenoproteins in general. Sorry to not be of more help...
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