Cloning--a novel idea

Michael Kolotila x3887 mkolotila at NECCADM1.NECC.MASS.EDU
Fri Aug 25 08:45:11 EST 1995

Good point.  Let's assume that circulating white blood cells have the 
germ line configuration, but certain are inactivated.  Then it becomes a 
matter, and not a trivial one, of re-activating those genes.  I would 
suppose then that the individual would be immunocompetent providing that 
the DNA donor was immunocompetent.  My $0.02 worth.

 Michael P. Kolotila, Ph.D.        * e-mail: mkolotila at   
 Biotechnology Program Coordinator *          
 Department of Natural Science     * voice :  508-374-3887
 Northern Essex Community College  *
 100 Elliott Way                   * fax   :  508-374-3723
 Haverhill, MA  01830-2399         *        

On 24 Aug 1995 matkisso at wrote:

> >> 
> > Human erythrocytes do not contain DNA, correct.  Other cells found 
> > in blood do.
> Point of curiosity:  Unless some rare circulating stem cell happened to be
> present, wouldn't the B and T cell DNA in the blood belong to committed cells
> whose antigen recognition repertoire has been determined?  Presuming you could
> clone the whole individual human, is it reasonable to think the clone would be,
> for all practical purposes, immunodeficient?

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