question about dna structure

Stephen J Williams willham at
Mon Jan 23 21:24:58 EST 1995

  I have a question regarding the conformational changes induced by pH on 
oligonucleotides.  I am using a Tris based buffer and am varying the pH 
from 7.0 to 9.0.  Are there any conformational changes (like conversion from
B-form to A-form with change in pH to a DNA duplex?  

Thank you 

Stephen Williams  at willham at

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