Help on Huntington's Chorea
David G. Kitaguchi
davidk at gdb.org
Fri Nov 3 11:27:05 EST 1995
In article o3q at muss.CIS.McMaster.CA, u9415136 at muss.cis.McMaster.CA (P. Pandya) writes:
>Hello. I am currently researching Huntington's Chorea as part of my
>studies. I'm not sure if this is the right place to ask, but I would
>greatly appreciate some help as to where to look for information
>regarding this disease. Things which I am looking for specifically are
>gene sequences, pedigree trees, and 1st-2nd year level explainations of the
>disease. Any method of internet information retrieval (ie. email, FTP)
>Thank you all for your time and help.
>u9415136 at muss.cis.mcmaster.ca
This place is as good as any to ask. Depending on what you are looking for,
I would recommend a possible search starting with OMIM (Online Mendelian
Inheritance in Man). The URL for your search would be:
Proving you have access to WWW. OMIM in general would be:
then choose "OMIM -- Online Mendelian Inheritance in Man"
In anycase you can start from the GDB Homepage, use OMIM to look up
Huntington's Chorea, and from the bottom of the OMIM document you can then
follow it to GDB (The Genome Data Base). There you will find information
about locus "LD" on 4p16.3. The information will be of probes, citations,
mutations, polymorphisms, DNAseq numbers (GenBank numbers), and even
mammalian homology information. These can all be followed to greater and
greater details of desquences, and contacts and so on. If you have any
questions about this or any of the methods involved in doing searches
like this, feel free to contact me at "help at gdb.org" for more information.
David Kitaguchi, Sr. User System Specialist WHOIS - DGK2
GDB/OMIM User Support Phone: (410) 955-9705
Johns Hopkins University School of Medicine FAX: (410) 614-0434
2024 E. Monument Street
Baltimore, MD 21205-2100
help at gdb.org
davidk at gdb.org
Try our E-mail Query Service just put "help" in the body of a
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The Human Genome Database GDB(TM)
An international collaboration in support of the
Human Genome Initiative hosted at
The Johns Hopkins University School of Medicine
Baltimore, Maryland USA
GDB (Genome Data Base)
GDB contains human gene mapping information. The data are acquired by direct
submission to GDB, entry by Human Genome Organization (HUGO) editors, and by
scanning of the scientific literature.
GDB stores and curates the following types of information:
. Loci Defined regions of the genome, ranging in size between a
single point and an extended region.
. Probes Reagents for detecting genes, DNA segments and their
. Maps Genetic or physical maps representing an ordered set of
elements (loci or probes) on a chromosome.
. Polymorphisms Heritable variations in the DNA sequence of loci, often useful
in genetic mapping experiments.
. Mutations Spontaneous sequence variations in loci, often responsible for
. Cell Lines Clonal mammalian cell lines which are useful for genomic
. Libraries Collections of DNA clones, often from specific regions of the
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