1 Brown/1 Blue eye
eddy at wol.wustl.edu
Thu Nov 30 15:32:50 EST 1995
In article <49bd5e$68e at decaxp.harvard.edu> robison at nucleus.harvard.edu (Keith Robison) writes:
>: I have a student who has one beautiful brown eye, and one beautiful blue
>: eye. Do any of you know the genetic/molecular mechanism behind this
>: phenomenon? Any idea how common it is? I would appreciate any
>: information, or references.
>Presumably your student is exhibiting genetic mosaicism...
>One possiblity is that the
>brown allele was inactivated by a somatic mutation; the other is
>loss of the brown allele via somatic recombination (I haven't
>a clue as to which has a higher frequency).
Another possibility is the early embryonic fusion of dizygotic
(fraternal) twins, I think.
- Sean Eddy
- Dept. of Genetics, Washington University School of Medicine
- eddy at genetics.wustl.edu
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