eHand/dHand and Cardiogenesis....bHLH rear their head again!!!
popa0206 at PO-Box.McGill.CA
Tue Feb 13 22:07:21 EST 1996
"Subclass of bHLH Proteins Required for Cardiac Morphogenesis"
Sriastava, Cjserjesi and Olson (Science,Vol 270 Dec 22, 1995)
I was wondering what the general response to this paper was.
I think many people may have been surprised to see a bHLH protein in cardiogenesis after such a
long unfruitful search by others in the past.
I know many people are betting on the GATA family of transcription factors as playing a major role in
cardiac muscle development.
ANy one have any opinions on this? Where would you go next.... DD-PCR to find the genes that the putative transcription
factors eHAND and dHAND activate or regulate?
Please post any comments to
dellaire at odyssee.net
popa0206 at po-box.mcgill.ca
as my local news feed for lack of a better word... "SUCKS!"
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