Scatchard Plots: Numerous Absurd Er
yur77 at glas.apc.org
Tue Jun 25 10:45:08 EST 1996
Note my paper describing several widespread errors in
performing Scatchard plot analysis.
The summary is below. Full text (format MS Word 6.0 for Win)
is available from: ftp://garbo.uwasa.fi/pc/science/crsaf_02.zip
ABSURD TRIVIAL ERRORS IN SCATCHARD PLOT ANALYSIS
Dmitriy K.Yuryev yur77 at glas.apc.org
Several types of widespread errors in performing Scatchard plot
analysis resulting in fatal distortions of calculated affinities are
surveyed more or less systematically. It appears that graphical
analysis of non-linear Scathard plot "by eye" is almost impossible;
and, moreover, results calculated by computer programs for affinity
analysis often require additional "interpretation".
Some of reported errors also definitely imply that data fabrication
is quite common practice in this field.
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