PG physiology at colinst.com
Wed Sep 4 08:38:08 EST 1996

First ever measurements of cardiac output in mice were performed by scientists of
Columbus Instruments. These measurements followed the thermodilution method using
Columbus Instruments Cardiomax cardiac output computer equipped with F #1
thermodilution microprobes. Measurements were performed by injection of 15
microliters of room temperature injectate (saline) into the vena cava through the right
external jugular vein. The thermodilution microprobe was inserted into the aortic arch
through the left carotid artery. Several subsequent measurements of cardiac output
can be performed at an interval of 2 to 3 minutes with consistent and repetitive results.
The same Cardiomax can also be used for measuring cardiac output of rats, as well as
larger animals. If you are interested to receive more information, please provide your
street address. I will be happy to mail you all information.


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