ANNOUNCEMENT: Release 2 of TREMBL, a protein sequence database supplementing

Rolf Apweiler apweiler at
Fri Feb 28 00:09:06 EST 1997

the SWISS-PROT Protein Sequence Data Bank


TREMBL is a protein sequence database supplementing the SWISS-PROT Protein
Sequence Data Bank. TREMBL contains the translations of all coding 
sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet
integrated in SWISS-PROT. TREMBL can be considered as a preliminary 
section of SWISS-PROT. For all TREMBL entries which should finally be 
upgraded to the standard SWISS-PROT quality, SWISS-PROT accession numbers 
have been assigned.


This TREMBL release is created from the EMBL Nucleotide Sequence Database
release 49 and contains 116'379 sequence entries, comprising 31'293'053 
amino acids. 

TREMBL is split in two main sections; SP-TREMBL and REM-TREMBL:

SP-TREMBL (SWISS-PROT TREMBL) contains the entries (96'757) which should be 
eventually incorporated into SWISS-PROT. SWISS-PROT accession numbers have 
been assigned for all SP-TREMBL entries. 

SP-TREMBL is organized in subsections:

fun.dat (Fungi):                3108 entries
hum.dat (Human):                4541 entries
inv.dat (Invertebrates):       13269 entries
mam.dat (Other Mammals):        1740 entries
mhc.dat (MHC proteins):         2307 entries
org.dat (Organelles):           6705 entries
phg.dat (Bacteriophages):        884 entries
pln.dat (Plants):               5699 entries
pro.dat (Prokaryotes):         23331 entries
rod.dat (Rodents):              4769 entries
vrl.dat (Viruses):             28150 entries
vrt.dat (Other Vertebrates):    2254 entries

REM-TREMBL (REMaining TREMBL) contains the entries (19'622) that we do 
not want to include in SWISS-PROT. 

Weekly cumulative updates of TREMBL will be available by anonymous FTP and 
>From the EBI SRS server from the beginning of March 1997 onwards.


FTP server:
SRS server:

TREMBL is also available on the SWISS-PROT CD-ROM.
SP-TREMBL is searchable on the FASTA server of the EBI and will be soon 
searchable on the BLITZ server of the EBI.


Rolf Apweiler, Sergio Contrino, Vivien Junker, Stephanie Kappus, 
Fiona Lang, Michele Magrane, Maria Jesus Martin, Nicoletta Mitaritonna 
and Claire O'Donovan at the EMBL Outstation - European Bioinformatics 
Institute (EBI) in Hinxton, UK;
Amos Bairoch and Alain Gateau at the Medical Biochemistry Department of 
the University of Geneva, Switzerland.

Rolf Apweiler                           | SWISS-PROT Coordinator
EMBL Outstation                         | Email:apweiler at
European Bioinformatics Institute (EBI) | URL:
Wellcome Trust Genome Campus, Hinxton   | Tel:  +44 (1223) 494435
Cambridge CB10 1SD, UK                  | Fax:  +44 (1223) 494968

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