ewi at gbf-braunschweig.de
Fri Feb 28 10:06:43 EST 1997
The new release 3.1 of the TRANSFAC database is now available at the
following WWW site:
(Wingender et al., 1997, Nucleic Acids Res. 25:265-268).
TRANSFAC is a database on eukaryotic transcription factors and their
binding sites. As new features, it now includes the complete amino acid
sequences of the transcription factors (FACTOR table) and links to the
Eukaryotic Promoter Database (EPD) in its SITE table. Moreover, the data
volume has increased comprising now 2080 FACTOR and 4362 SITE entries.
As a new search option, you may retrieve factors by their molecular weight.
Moreover, you will find a SRS5 version which offers additional retrieval
options for the TRANSFAC tables, for EMBL, SwissProt, PIR,
(for this, we
give credit to Thure Etzold, EBI, Hinxton).
As for release 3.0, there are also extensive links with TRRD (Transcription
Regulatory Regio Database) and COMPEL (Composite Elements Database),
maintained at the Institute of Cytology and Genetics (ICG, Novosibirsk,
Russia: N. A. Kolchanov/A. Kel et al.).
The sequence information contained in the SITE table is used by
PatternSearch 1.0 for interactive sequence scanning for potential TF
An updated library of matrices for transcription factor binding sites will
be provided very soon which can be used for sequence analysis with
MatInspector release 2.0 (Quandt et al., 1995, Nucleic Acids Res.
This tool is available at
(Thomas Werner and coworkers).
Please, forward this mail to your colleagues which may be interested in
using these tools
On behalf of the TRANSFAC team:
GBF - Braunschweig, February 28, 1997
Dr. Edgar Wingender
Molecular Bioinformatics of Gene Regulation
Mascheroder Weg 1
Phone 49 - 531 - 6181-427
FAX 49 - 531 - 6181-266
More information about the Bioforum