Factor V Leiden

Rolf Marteijn rolf at lx.student.wau.nl
Fri Jun 6 19:34:57 EST 1997


Hi,

Tremblay wrote:
> 
> Hello, I 've got a question about human genetics.  A good friend of mine
> was recently diagnosed with the genetic mutatioin "Factor V. Leiden".
> Even though 5% of the North American population has this, the doctors
> here don't know much about it, and I can't find all that much relevant
> information either.  I do know that it has to do with a resistance to
> activated protein C, and that it increases chances of thrombotic
> episodes, but other than that, I can't find much.  I was wondering if
> anyone knows anything about what exactly it is, and ways that it can be
> treated.  Thanks for your time.

On MEDLINE/PUBMED there are >100 publications featuring Factor V Leiden.
Point your browser to:
http://www4.ncbi.nlm.nih.gov/PubMed/medline.html

BTW Leiden is the name of the city where this mutation was found 
(University Leiden, The Netherlands).

Regards

Rolf



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