Factor V Leiden

[Andreas Matern]

In article <339603BD.2C9A at agt.net>, trem_bro at agt.net wrote:

> Hello, I 've got a question about human genetics.  A good friend of mine
> was recently diagnosed with the genetic mutatioin "Factor V. Leiden". 
> Even though 5% of the North American population has this, the doctors
> here don't know much about it, and I can't find all that much relevant
> information either.  I do know that it has to do with a resistance to
> activated protein C, and that it increases chances of thrombotic
> episodes, but other than that, I can't find much.  I was wondering if
> anyone knows anything about what exactly it is, and ways that it can be
> treated.  Thanks for your time.

Although not a human geneticist, I found a few WWW references using Excite
(http://www/excite.com/):

http://www.bloodjournal.org/abs89_8/33xx0050.htm
http://www.path.sunysb.edu/news/labnews/vol15num1/factorvleiden.html
http://www3.ncbi.nlm.nih.gov:80/htbin-post/Omim/dispmim?227400#AllelicVariant0001

That should be a place to start....

-- 
Andreas Matern
alm13 at cornell.edu
266 Emerson Hall
Dept of Plant Breeding and Biometry
Cornell University
Ithaca, NY  14853